Across TCGA cell cohorts, KNTC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,695 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KNTC1-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Centriole replication, and DNA replication. Each is linked with KNTC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both KNTC1-to-partner and partner-to-KNTC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KNTC1→partner) and Y-score (partner→KNTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.121	+1.428	.001	<.001	3	20
OESOPHAGUS	Centriole replication →	+0.110	+0.935	<.001	<.001	3	20
BONE	DNA replication →	+0.113	+1.229	.002	.002	3	20
OESOPHAGUS	DNA-templated DNA replication →	+0.158	+1.257	.001	.001	3	20
OESOPHAGUS	Double-strand break repair via homologous recombination →	+0.092	+1.049	<.001	<.001	3	20
BONE	Recombinational repair →	+0.094	+1.281	<.001	.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,695 associations by consensus.

Exploration

KNTC1 survival (RNA) · tumor vs normal (RNA) · all KNTC1 data types