KNSTRN

Across TCGA patient cohorts, KNSTRN protein abundance is significantly associated with the RNA expression of many other genes, with 16,630 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KNSTRN-associated genes across cancer lineages are CENPA, HJURP, and DLGAP5. Each is linked with KNSTRN in more than 6 cancer types. Because this analysis shows association rather than direction, both KNSTRN-to-partner and partner-to-KNSTRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KNSTRN versus CENPA in LUAD, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KNSTRN→partner) and Y-score (partner→KNSTRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CENPA →	+1.551	+0.740	<.001	.003	3	7
LUAD	HJURP →	+1.623	+0.853	<.001	<.001	3	7
LUAD	DLGAP5 →	+1.227	+0.764	.001	<.001	3	7
OV	PIF1 →	+1.341	+0.950	.001	.001	3	7
LUAD	KIF2C →	+1.689	+0.873	<.001	<.001	3	7
LUAD	CCNB2 →	+1.381	+0.885	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,630 associations by consensus.

KNSTRN vs CENPA — LUAD

Explore this scatter interactively →