Across TCGA pan-cancer cohorts, KNOP1P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KNOP1P3’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where KNOP1P3 RNA is repressed in tumor relative to normal tissue. In most cancer types KNOP1P3 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC and LUAD are the cancer types where KNOP1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KNOP1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.023	.044	1	view →
LUAD	All	All	−0.021	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: KNOP1P3 RNA expression & survival · all KNOP1P3 data types