lysine rich nucleolar protein 1 pseudogene 2Genealiases: []
Q-omics provides the consensus-scored KNOP1P2 profile across patient tissues and cancer cell-line models. KNOP1P2 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, KNOP1P2 is differentially expressed in 8, with the highest sampling consensus in HNSC. Additionally, KNOP1P2 RNA expression shows 17,416 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight HNSC, and TGCT as cancer lineages where KNOP1P2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KNOP1P2 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KNOP1P2 survival associations across molecular data types. KNOP1P2 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KNOP1P2 RNA expression–survival associations across cancer types. High KNOP1P2 expression shows unfavorable associations in THCA, CESC, LIHC and STAD, but favorable associations in HNSC and LUAD. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify HNSC as the clearest survival context for KNOP1P2 RNA expression.
This table summarizes KNOP1P2 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in LIHC for RNA.
This table ranks reproducible tumor–normal expression differences for KNOP1P2. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KNOP1P2 shows lower tumor expression in THCA and higher tumor expression in HNSC, LIHC, CHOL, BRCA and READ. The HNSC box plot shows higher KNOP1P2 RNA expression in tumor versus normal tissue (log2 FC = +0.049, t-test p < 0.001).
This table shows molecular features associated with KNOP1P2 in patient tissues and cancer cell lines. In patient samples, KNOP1P2 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
