KNL1

Across TCGA cell cohorts, KNL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,549 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KNL1-associated GO terms across cancer lineages are Meiotic nuclear division, Mitotic nuclear division, and Meiotic cell cycle process. Each is linked with KNL1 in more than 19 cancer types. Because this analysis shows association rather than direction, both KNL1-to-partner and partner-to-KNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic nuclear division grouped by KNL1-low versus KNL1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KNL1→partner) and Y-score (partner→KNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Meiotic nuclear division →	+0.089	+1.521	.002	<.001	3	20
OESOPHAGUS	Mitotic nuclear division →	+0.149	+1.575	.001	<.001	3	20
OESOPHAGUS	Meiotic cell cycle process →	+0.094	+1.373	<.001	.001	3	20
URINARY_TRACT	Positive regulation of chromosome condensation →	+0.278	+1.465	<.001	<.001	3	20
OESOPHAGUS	Nuclear division →	+0.132	+1.608	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.202	+1.493	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,549 associations by consensus.

Meiotic nuclear division by KNL1 expression — OESOPHAGUS

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