KNDC1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KNDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,447 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible KNDC1-associated GO terms across cancer lineages are Primary alcohol biosynthetic process, Neuron-glial cell signaling, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with KNDC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both KNDC1-to-partner and partner-to-KNDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Primary alcohol biosynthetic process grouped by KNDC1-low versus KNDC1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KNDC1→partner) and Y-score (partner→KNDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEPrimary alcohol biosynthetic process →-0.310-0.681<.001<.00139
SOFT_TISSUENeuron-glial cell signaling →+1.086+0.815<.001.00138
UPPER_AERODIGESTIVE_TRACTPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.123+0.756.002.00338
OESOPHAGUSNegative regulation of myoblast fusion →+0.160+1.041.003<.00138
UPPER_AERODIGESTIVE_TRACTLipoprotein localization →+0.086+0.606<.001.00138
UPPER_AERODIGESTIVE_TRACTSCF-dependent proteasomal ubiquitin-dependent protein catabolic process →+0.042+0.672<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,447 associations by consensus.

Primary alcohol biosynthetic process by KNDC1 expression — SOFT_TISSUE

Box plot of Primary alcohol biosynthetic process in KNDC1-low vs KNDC1-high samples in SOFT_TISSUE.

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Exploration