Across TCGA cell cohorts, KLRK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,672 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KLRK1-associated GO terms across cancer lineages are Positive regulation of natural killer cell mediated immunity, Regulation of mRNA splicing, via spliceosome, and Positive regulation of protein deubiquitination. Each is linked with KLRK1 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLRK1-to-partner and partner-to-KLRK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRK1→partner) and Y-score (partner→KLRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of natural killer cell mediated immunity →	-0.129	-0.668	.003	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.079	+0.343	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein deubiquitination →	+0.120	+0.355	.005	.004	3	6
UPPER_AERODIGESTIVE_TRACT	Endosome membrane tubulation →	+0.111	+0.554	<.001	<.001	3	5
BLOOD_Lymphoma	Natural killer cell mediated immunity →	-0.057	-1.514	.006	.008	2	6
BREAST	Positive regulation of signal transduction by p53 class mediator →	+0.074	+0.235	.004	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,672 associations by consensus.

Exploration

KLRK1 survival (RNA) · tumor vs normal (RNA) · all KLRK1 data types