Across TCGA cell cohorts, KLRK1 mutation is significantly associated with the mutation status of many other genes, with 286 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KLRK1-associated genes across cancer lineages are SLC12A3, JPH1, and ATP6V1B1. Each is linked with KLRK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLRK1-to-partner and partner-to-KLRK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRK1→partner) and Y-score (partner→KLRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC12A3 →	+2.422	+4.050	.004	.004	1	2
BLOOD_Lymphoma	JPH1 →	+3.847	+5.108	.001	.001	1	2
BLOOD_Lymphoma	ATP6V1B1 →	+5.584	+5.014	.003	.003	1	2
BLOOD_Lymphoma	TEX14 →	+4.584	+4.584	.007	.007	1	2
BLOOD_Lymphoma	MYRF →	+4.584	+4.584	.007	.007	1	2
BLOOD_Lymphoma	STAB2 →	+2.710	+4.203	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 286 associations by consensus.

Exploration

KLRK1 survival (RNA) · tumor vs normal (RNA) · all KLRK1 data types