KLRD1

Across TCGA cell cohorts, KLRD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 580 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KLRD1-associated GO terms across cancer lineages are Proteasomal ubiquitin-independent protein catabolic process, Viral life cycle, and Polysaccharide catabolic process. Each is linked with KLRD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both KLRD1-to-partner and partner-to-KLRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasomal ubiquitin-independent protein catabolic process grouped by KLRD1-low versus KLRD1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRD1→partner) and Y-score (partner→KLRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Proteasomal ubiquitin-independent protein catabolic process →	+0.053	+0.136	.002	.003	3	6
LARGE_INTESTINE	Viral life cycle →	+0.042	+0.037	.004	.002	3	5
LARGE_INTESTINE	Polysaccharide catabolic process →	+0.064	+0.026	<.001	.001	3	5
LARGE_INTESTINE	Substrate adhesion-dependent cell spreading →	+0.091	+0.041	.001	.005	3	5
LARGE_INTESTINE	Glycogen catabolic process →	+0.063	+0.026	<.001	.001	3	5
LARGE_INTESTINE	Glucan catabolic process →	+0.064	+0.026	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 580 associations by consensus.

Proteasomal ubiquitin-independent protein catabolic process by KLRD1 expression — CNS

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