KLRC4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KLRC4 mutation is significantly associated with the RNA expression of many other genes, with 570 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLRC4-associated genes across cancer lineages are CAPZBP1, TRAJ11, and RN7SKP286. Each is linked with KLRC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLRC4-to-partner and partner-to-KLRC4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRC4→partner) and Y-score (partner→KLRC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCAPZBP1 →+0.595+5.080<.001.00832
UCECTRAJ11 →+0.434+2.354.002<.00132
UCECRN7SKP286 →+0.065+4.645<.001<.00132
BLCAPOTED →+0.013+5.444.002.00231
BLCARN7SKP115 →+0.291+4.497<.001.00931
BLCAMIR32 →+0.897+4.497<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 570 associations by consensus.

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