KLRC2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KLRC2 mutation is significantly associated with the RNA expression of many other genes, with 699 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLRC2-associated genes across cancer lineages are MYEOV, ANKHD1, and H3P38. Each is linked with KLRC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLRC2-to-partner and partner-to-KLRC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRC2→partner) and Y-score (partner→KLRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMYEOV →+1.727+3.459<.001.00532
UCECANKHD1 →+0.419+3.507<.001.00232
LIHCH3P38 →+0.138+5.268<.001.00631
SKCMCASKP1 →+0.041+3.487.003.00531
SKCMLINC02559 →+0.094+4.039<.001.00931
SKCMMTND2P6 →+0.024+3.776<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 699 associations by consensus.

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