KLRA1P

Across TCGA patient cohorts, KLRA1P mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLRA1P-associated genes across cancer lineages are JNK_pT183_Y185, Notch1, and Rictor_pT1135. Each is linked with KLRA1P in more than 1 cancer types. Because this analysis shows association rather than direction, both KLRA1P-to-partner and partner-to-KLRA1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by KLRA1P-low versus KLRA1P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRA1P→partner) and Y-score (partner→KLRA1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.218	-3.000	.018	.036	3	1
UCEC	Notch1 →	+0.275	+3.013	<.001	.018	3	1
UCEC	Rictor_pT1135 →	-0.130	-3.169	.021	.020	3	1
UCEC	Tuberin →	+0.410	+3.169	.005	.020	3	1
UCEC	Bim →	-0.288	-3.169	.045	.020	3	1
UCEC	EGFR_pY1068 →	-0.299	-3.169	.030	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

JNK_pT183_Y185 by KLRA1P expression — UCEC

Explore this box plot interactively →