KLKB1

Across TCGA patient cohorts, KLKB1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,327 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLKB1-associated genes across cancer lineages are FLT1, SERPINE1, and F13A1. Each is linked with KLKB1 in more than 7 cancer types. Because this analysis shows association rather than direction, both KLKB1-to-partner and partner-to-KLKB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLKB1 versus FLT1 in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLKB1→partner) and Y-score (partner→KLKB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FLT1 →	+0.960	+0.855	<.001	<.001	3	8
OV	SERPINE1 →	+1.418	+0.558	.002	.002	3	8
GBM	F13A1 →	+1.711	+0.529	<.001	<.001	3	8
BRCA	CD93 →	+0.866	+0.584	<.001	<.001	3	8
OV	VEGFC →	+1.068	+0.697	<.001	<.001	3	8
CCRCC	AVPR1A →	+0.891	+0.523	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,327 associations by consensus.

KLKB1 vs FLT1 — OV

Explore this scatter interactively →