KLK7

Across TCGA patient cohorts, KLK7 RNA expression is significantly associated with the RNA expression of many other genes, with 11,499 significant associations in total. THYM shows the largest number of these associations.

The most reproducible KLK7-associated genes across cancer lineages are KLK6, KLK5, and KLK10. Each is linked with KLK7 in more than 27 cancer types. Because this analysis shows association rather than direction, both KLK7-to-partner and partner-to-KLK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLK7 versus KLK6 in STAD, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK7→partner) and Y-score (partner→KLK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	KLK6 →	+3.686	+2.958	<.001	<.001	3	28
ESCA	KLK5 →	+3.579	+3.324	<.001	<.001	3	27
THCA	KLK10 →	+3.609	+3.937	<.001	<.001	3	27
THYM	KLK8 →	+5.167	+2.317	<.001	<.001	3	26
ESCA	KRT16 →	+4.400	+2.727	<.001	<.001	3	21
LGG	RASAL1 →	+2.047	+1.453	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,499 associations by consensus.

KLK7 vs KLK6 — STAD

Explore this scatter interactively →