KLK7

Across TCGA patient cohorts, KLK7 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,628 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLK7-associated proteins across cancer lineages are KLK6, KRT23, and SERPINB5. Each is linked with KLK7 in more than 5 cancer types. Because this analysis shows association rather than direction, both KLK7-to-partner and partner-to-KLK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLK7 versus KLK6 in LSCC, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK7→partner) and Y-score (partner→KLK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KLK6 →	+1.824	+2.275	<.001	<.001	3	6
PDAC	KRT23 →	+1.083	+1.947	<.001	<.001	3	6
LSCC	SERPINB5 →	+1.272	+1.948	<.001	<.001	3	5
HNSC	EPS8L1 →	+0.701	+1.931	<.001	<.001	3	5
UCEC	KRT16 →	+1.740	+1.511	<.001	<.001	3	5
UCEC	KRT5_S82 →	+1.306	+1.361	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,628 associations by consensus.

KLK7 vs KLK6 — LSCC

Explore this scatter interactively →