KLK7

Across TCGA cell cohorts, KLK7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,007 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible KLK7-associated GO terms across cancer lineages are Antimicrobial peptide production, Antimicrobial peptide biosynthetic process, and Antibacterial peptide production. Each is linked with KLK7 in more than 15 cancer types. Because this analysis shows association rather than direction, both KLK7-to-partner and partner-to-KLK7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antimicrobial peptide production grouped by KLK7-low versus KLK7-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK7→partner) and Y-score (partner→KLK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Antimicrobial peptide production →	+2.068	+4.439	<.001	<.001	3	16
STOMACH	Antimicrobial peptide biosynthetic process →	+2.068	+4.439	<.001	<.001	3	16
STOMACH	Antibacterial peptide production →	+2.068	+4.439	<.001	<.001	3	16
STOMACH	Antibacterial peptide biosynthetic process →	+2.068	+4.439	<.001	<.001	3	16
STOMACH	Negative regulation of hippocampal neuron apoptotic process →	+1.378	+2.330	<.001	.004	3	10
PANCREAS	Regulation of cardiac muscle cell action potential →	+0.113	+1.593	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,007 associations by consensus.

Antimicrobial peptide production by KLK7 expression — STOMACH

Explore this box plot interactively →