KLK13

Across TCGA patient cohorts, KLK13 protein abundance is significantly associated with the RNA expression of many other genes, with 5,393 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KLK13-associated genes across cancer lineages are IL17C, MMP7, and CNGA3. Each is linked with KLK13 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLK13-to-partner and partner-to-KLK13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLK13 versus IL17C in LUAD, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK13→partner) and Y-score (partner→KLK13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IL17C →	+1.235	+1.409	<.001	.003	3	2
LUAD	MMP7 →	-2.888	-1.973	<.001	.009	3	2
LUAD	CNGA3 →	+5.384	+2.298	<.001	.003	3	2
LUAD	TIAM2 →	-0.561	-1.861	.005	.006	3	2
LUAD	KLK11 →	+6.304	+2.493	<.001	.001	3	2
BRCA	LRRC26 →	+1.981	+1.493	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,393 associations by consensus.

KLK13 vs IL17C — LUAD

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