KLK13

Across TCGA cell cohorts, KLK13 RNA expression is significantly associated with the go_rna of many other GO terms, with 679 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KLK13-associated GO terms across cancer lineages are Copulation, Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, and Negative regulation of vascular endothelial growth factor signaling pathway. Each is linked with KLK13 in more than 4 cancer types. Because this analysis shows association rather than direction, both KLK13-to-partner and partner-to-KLK13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copulation grouped by KLK13-low versus KLK13-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK13→partner) and Y-score (partner→KLK13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Copulation →	+0.641	+0.070	.005	.007	3	5
OVARY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.063	-1.020	<.001	.005	3	5
STOMACH	Negative regulation of vascular endothelial growth factor signaling pathway →	+0.158	+0.878	.003	.007	3	5
URINARY_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.066	+0.113	.004	.009	3	5
LUNG_SCLC	Epidermis development →	+0.102	+0.503	<.001	.005	3	5
BREAST	Cell junction assembly →	+0.041	+0.219	.004	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 679 associations by consensus.

Copulation by KLK13 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →