KLK10

Across TCGA patient cohorts, KLK10 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,139 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLK10-associated proteins across cancer lineages are KLK11, SERPINB5, and EPS8L1. Each is linked with KLK10 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLK10-to-partner and partner-to-KLK10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLK10 versus KLK11 in LSCC, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK10→partner) and Y-score (partner→KLK10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KLK11 →	+1.744	+2.449	<.001	<.001	3	7
BRCA	SERPINB5 →	+1.823	+1.579	<.001	<.001	3	5
HNSC	EPS8L1 →	+0.738	+1.773	<.001	<.001	3	5
OV	S100A16 →	+0.775	+2.171	<.001	<.001	3	4
BRCA	MSLN →	+1.067	+1.812	.008	.005	3	4
OV	MYH14 →	+0.587	+1.783	.005	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,139 associations by consensus.

KLK10 vs KLK11 — LSCC

Explore this scatter interactively →