KLK10

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KLK10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,290 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KLK10-associated GO terms across cancer lineages are Antimicrobial peptide production, Antimicrobial peptide biosynthetic process, and Antibacterial peptide production. Each is linked with KLK10 in more than 13 cancer types. Because this analysis shows association rather than direction, both KLK10-to-partner and partner-to-KLK10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antimicrobial peptide production grouped by KLK10-low versus KLK10-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK10→partner) and Y-score (partner→KLK10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYAntimicrobial peptide production →+1.582+3.844<.001<.001314
OVARYAntimicrobial peptide biosynthetic process →+1.582+3.844<.001<.001314
OVARYAntibacterial peptide production →+1.582+3.844<.001<.001314
OVARYAntibacterial peptide biosynthetic process →+1.582+3.844<.001<.001314
URINARY_TRACTPositive regulation of iron ion transport →+1.839+2.359<.001.004310
URINARY_TRACTPositive regulation of iron ion transmembrane transport →+1.839+2.359<.001.004310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,290 associations by consensus.

Antimicrobial peptide production by KLK10 expression — OVARY

Box plot of Antimicrobial peptide production in KLK10-low vs KLK10-high samples in OVARY.

Explore this box plot interactively →

Exploration