Across TCGA patient cohorts, KLHL9 protein abundance is significantly associated with the RNA expression of many other genes, with 2,826 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL9-associated genes across cancer lineages are LYVE1, ARL14EPP1, and STIM1-AS1. Each is linked with KLHL9 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHL9-to-partner and partner-to-KLHL9 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL9→partner) and Y-score (partner→KLHL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LYVE1 →	+0.917	+0.296	.002	.003	3	2
LUAD	ARL14EPP1 →	-0.390	-0.290	.004	.001	3	2
LUAD	STIM1-AS1 →	-0.371	-0.290	.002	.004	3	2
LSCC	LINC02646 →	-0.617	-0.325	.002	<.001	3	2
CCRCC	HIGD1AP13 →	-0.436	-0.736	.001	.001	3	2
OV	DLAT →	+0.770	+1.018	.007	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,826 associations by consensus.

Exploration

KLHL9 survival (RNA) · tumor vs normal (RNA) · all KLHL9 data types