Across TCGA patient cohorts, KLHL9 mutation is significantly associated with the RNA expression of many other genes, with 2,713 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLHL9-associated genes across cancer lineages are FXYD6P1, RNA5SP65, and CCDC58P2. Each is linked with KLHL9 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHL9-to-partner and partner-to-KLHL9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL9→partner) and Y-score (partner→KLHL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FXYD6P1 →	+0.167	+3.473	<.001	.006	3	3
STAD	RNA5SP65 →	+0.504	+4.520	.001	.005	3	2
LGG	CCDC58P2 →	+0.126	+5.846	<.001	.003	3	2
LGG	MIR4654 →	+0.487	+5.760	<.001	.003	3	2
READ	APOOP2 →	+0.655	+5.039	<.001	.008	3	2
UCEC	LINC02084 →	+0.313	+2.032	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,713 associations by consensus.

Exploration

KLHL9 survival (RNA) · tumor vs normal (RNA) · all KLHL9 data types