KLHL9

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KLHL9 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLHL9-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, eIF4E, and INPP4B. Each is linked with KLHL9 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHL9-to-partner and partner-to-KLHL9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL9→partner) and Y-score (partner→KLHL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAcetyl-a-Tubulin-Lys40 →+0.432+1.710.012.02533
UCECeIF4E →+0.205+3.713.004<.00132
UCECINPP4B →-0.295-2.222.007.00932
UCECATM →-0.663-1.807<.001.00432
UCECBax →+0.228+1.807.005.00432
UCECCDK1 →+0.129+1.247.011.04532
Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

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