KLHL42

Across TCGA patient cohorts, KLHL42 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,979 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL42-associated proteins across cancer lineages are PSMB10, IL18, and CASP10. Each is linked with KLHL42 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLHL42-to-partner and partner-to-KLHL42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL42 versus PSMB10 in LSCC, with a Pearson correlation of -0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL42→partner) and Y-score (partner→KLHL42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PSMB10 →	-0.425	-0.683	<.001	<.001	3	7
HNSC	IL18 →	-1.002	-0.947	<.001	<.001	3	6
GBM	CASP10 →	-0.498	-0.325	<.001	<.001	3	6
GBM	DOCK8 →	-0.458	-0.325	<.001	<.001	3	6
GBM	MYO1G →	-0.697	-0.403	<.001	<.001	3	5
LSCC	GTF3C4 →	+0.312	+0.494	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,979 associations by consensus.

KLHL42 vs PSMB10 — LSCC

Explore this scatter interactively →