KLHL42

Across TCGA patient cohorts, KLHL42 protein abundance is significantly associated with the RNA expression of many other genes, with 5,104 significant associations in total. COAD shows the largest number of these associations.

The most reproducible KLHL42-associated genes across cancer lineages are CRYAB, BACH2, and FILIP1L. Each is linked with KLHL42 in more than 3 cancer types. Because this analysis shows association rather than direction, both KLHL42-to-partner and partner-to-KLHL42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL42 versus CRYAB in COAD, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL42→partner) and Y-score (partner→KLHL42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CRYAB →	+1.545	+0.644	<.001	<.001	3	4
UCEC	BACH2 →	+0.465	+0.306	.002	<.001	3	4
CCRCC	FILIP1L →	+0.889	+0.533	.008	.008	3	4
COAD	MSRB3 →	+1.408	+0.643	<.001	<.001	3	4
UCEC	RASSF8-AS1 →	+0.586	+0.307	.005	.002	3	4
CCRCC	MYOCD-AS1 →	+1.339	+0.644	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,104 associations by consensus.

KLHL42 vs CRYAB — COAD

Explore this scatter interactively →