KLHL42

Across TCGA cell cohorts, KLHL42 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLHL42-associated genes across cancer lineages are DCD and PROP1. Each is linked with KLHL42 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL42-to-partner and partner-to-KLHL42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCD grouped by KLHL42-low versus KLHL42-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL42→partner) and Y-score (partner→KLHL42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DCD →	+1.446	+5.643	<.001	.002	3	1
BLOOD_Leukemia	PROP1 →	+0.023	+3.874	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

DCD by KLHL42 expression — LUNG_SCLC

Explore this box plot interactively →