KLHL4

Across TCGA patient cohorts, KLHL4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,552 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KLHL4-associated proteins across cancer lineages are ZYX, PDLIM3, and ZCCHC24. Each is linked with KLHL4 in more than 7 cancer types. Because this analysis shows association rather than direction, both KLHL4-to-partner and partner-to-KLHL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL4 versus ZYX in UCEC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL4→partner) and Y-score (partner→KLHL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZYX →	+0.529	+0.572	<.001	<.001	3	8
UCEC	PDLIM3 →	+1.098	+0.581	<.001	<.001	3	8
OV	ZCCHC24 →	+1.003	+1.039	<.001	.002	3	8
UCEC	TLN1 →	+0.488	+0.555	<.001	<.001	3	8
UCEC	DAB2 →	+0.376	+0.476	<.001	<.001	3	8
OV	PDLIM5 →	+0.875	+0.994	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,552 associations by consensus.

KLHL4 vs ZYX — UCEC

Explore this scatter interactively →