KLHL38

Across TCGA patient cohorts, KLHL38 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,162 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KLHL38-associated GO terms across cancer lineages are Actomyosin structure organization, Protein autophosphorylation, and Muscle cell development. Each is linked with KLHL38 in more than 25 cancer types. Because this analysis shows association rather than direction, both KLHL38-to-partner and partner-to-KLHL38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actomyosin structure organization grouped by KLHL38-low versus KLHL38-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL38→partner) and Y-score (partner→KLHL38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Actomyosin structure organization →	+0.045	+0.465	<.001	<.001	3	26
ESCA	Protein autophosphorylation →	+0.048	+0.362	<.001	<.001	3	25
UCS	Muscle cell development →	+0.067	+1.711	<.001	<.001	3	24
ESCA	Fat cell differentiation →	+0.037	+0.353	<.001	<.001	3	24
ESCA	Regulation of actin filament organization →	+0.052	+0.387	<.001	<.001	3	23
SCLC	Actin filament bundle organization →	+0.071	+0.217	<.001	.004	2	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,162 associations by consensus.

Actomyosin structure organization by KLHL38 expression — ESCA

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