KLHL38

Across TCGA cell cohorts, KLHL38 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,752 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KLHL38-associated GO terms across cancer lineages are Wound healing, Motile cilium assembly, and Keratinocyte activation. Each is linked with KLHL38 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLHL38-to-partner and partner-to-KLHL38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Wound healing grouped by KLHL38-low versus KLHL38-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL38→partner) and Y-score (partner→KLHL38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Wound healing →	+0.055	+0.065	.003	.007	3	7
UPPER_AERODIGESTIVE_TRACT	Motile cilium assembly →	-0.049	-0.114	<.001	<.001	3	7
SOFT_TISSUE	Keratinocyte activation →	+0.761	+0.095	.002	.003	3	7
CNS	Response to activity →	+0.056	+0.256	<.001	.003	3	7
SOFT_TISSUE	Lipoprotein biosynthetic process →	+0.061	+0.155	.007	.008	3	7
BREAST	Response to denervation involved in regulation of muscle adaptation →	+0.157	+0.750	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,752 associations by consensus.

Wound healing by KLHL38 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →