Across TCGA patient cohorts, KLHL34 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,292 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLHL34-associated proteins across cancer lineages are NOLC1_S538, PCLO_S906, and PDE4DIP_S1321. Each is linked with KLHL34 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHL34-to-partner and partner-to-KLHL34 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL34→partner) and Y-score (partner→KLHL34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NOLC1_S538 →	-0.495	-0.304	<.001	<.001	3	3
HNSC	PCLO_S906 →	+0.831	+0.266	<.001	.002	3	3
HNSC	PDE4DIP_S1321 →	+0.786	+0.461	<.001	<.001	3	3
HNSC	MYEF2_S17 →	+1.109	+0.411	<.001	<.001	3	3
GBM	MYOF →	-0.505	-0.317	<.001	<.001	3	3
GBM	PIP5K1C →	+0.254	+0.249	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,292 associations by consensus.

Exploration

KLHL34 survival (RNA) · tumor vs normal (RNA) · all KLHL34 data types