Across TCGA cell cohorts, KLHL34 RNA expression is significantly associated with the RNA expression of many other genes, with 2,986 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KLHL34-associated genes across cancer lineages are CNKSR2, OR52L1, and OR10J3. Each is linked with KLHL34 in more than 9 cancer types. Because this analysis shows association rather than direction, both KLHL34-to-partner and partner-to-KLHL34 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL34→partner) and Y-score (partner→KLHL34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	CNKSR2 →	+2.115	+0.058	<.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	OR52L1 →	+0.052	+0.009	<.001	.002	3	4
STOMACH	OR10J3 →	+0.128	+0.013	<.001	<.001	3	3
LUNG_NSCLC_LUSC	MAGEE2 →	+0.077	+0.015	<.001	.007	3	3
UPPER_AERODIGESTIVE_TRACT	DPRX →	+0.123	+0.007	.009	.007	3	3
LUNG_SCLC	MAGEL2 →	+1.209	+0.276	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,986 associations by consensus.

Exploration

KLHL34 survival (RNA) · tumor vs normal (RNA) · all KLHL34 data types