Across TCGA cell cohorts, KLHL34 RNA expression is significantly associated with the go_rna of many other GO terms, with 760 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KLHL34-associated GO terms across cancer lineages are Dosage compensation by inactivation of X chromosome, Positive regulation of RNA export from nucleus, and Positive regulation of response to oxidative stress. Each is linked with KLHL34 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLHL34-to-partner and partner-to-KLHL34 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL34→partner) and Y-score (partner→KLHL34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Dosage compensation by inactivation of X chromosome →	+0.079	+0.017	.004	.006	3	7
LUNG_SCLC	Positive regulation of RNA export from nucleus →	+0.083	+0.280	<.001	<.001	3	5
LUNG_NSCLC_LUSC	Positive regulation of response to oxidative stress →	+0.186	+0.012	<.001	.008	3	4
BLOOD_Leukemia	Nucleic acid catabolic process →	+0.028	+0.018	.003	.002	2	5
LUNG_NSCLC_LUSC	Regulation of lipoprotein metabolic process →	+0.139	+0.020	<.001	.008	3	4
LUNG_SCLC	mRNA alternative polyadenylation →	+0.075	+0.294	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 760 associations by consensus.

Exploration

KLHL34 survival (RNA) · tumor vs normal (RNA) · all KLHL34 data types