Across TCGA patient cohorts, KLHL32 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,412 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLHL32-associated proteins across cancer lineages are PTBP2, PRUNE1, and DDAH1. Each is linked with KLHL32 in more than 5 cancer types. Because this analysis shows association rather than direction, both KLHL32-to-partner and partner-to-KLHL32 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL32→partner) and Y-score (partner→KLHL32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PTBP2 →	+0.997	+0.471	<.001	<.001	3	6
LSCC	PRUNE1 →	+0.410	+0.493	.003	.002	3	6
PDAC	DDAH1 →	+0.498	+0.328	<.001	<.001	3	6
OV	WDR19 →	+0.336	+0.670	.001	.004	3	5
LSCC	LIMA1_S490 →	-0.505	-0.464	.001	<.001	3	5
UCEC	OSCP1 →	+0.426	+0.789	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,412 associations by consensus.

Exploration

KLHL32 survival (RNA) · tumor vs normal (RNA) · all KLHL32 data types