KLHL21

Across TCGA cell cohorts, KLHL21 RNA expression is significantly associated with the RNA expression of many other genes, with 11,305 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KLHL21-associated genes across cancer lineages are MFN2, LUZP1, and EMC1. Each is linked with KLHL21 in more than 15 cancer types. Because this analysis shows association rather than direction, both KLHL21-to-partner and partner-to-KLHL21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL21 versus MFN2 in BLOOD_Lymphoma, with a Pearson correlation of 0.47.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL21→partner) and Y-score (partner→KLHL21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MFN2 →	+0.980	+1.105	<.001	<.001	3	16
LARGE_INTESTINE	LUZP1 →	+1.255	+1.115	<.001	<.001	3	15
BREAST	EMC1 →	+1.211	+1.309	<.001	<.001	3	15
SKIN	ATAD3A →	+1.406	+1.091	<.001	<.001	3	14
BLOOD_Lymphoma	DNAJC11 →	+1.228	+1.197	<.001	<.001	3	14
BREAST	KIAA2013 →	+0.949	+1.005	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,305 associations by consensus.

KLHL21 vs MFN2 — BLOOD_Lymphoma

Explore this scatter interactively →