Across TCGA patient cohorts, KLHL17 protein abundance is significantly associated with the RNA expression of many other genes, with 211 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KLHL17-associated genes across cancer lineages are DOK5, NOMO3, and NOMO1. Each is linked with KLHL17 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL17-to-partner and partner-to-KLHL17 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL17→partner) and Y-score (partner→KLHL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DOK5 →	+0.810	+0.526	.004	.002	3	1
PDAC	NOMO3 →	-0.856	-0.424	<.001	.006	3	1
PDAC	NOMO1 →	-0.462	-0.490	.003	<.001	3	1
PDAC	APBA1 →	+0.574	+0.485	.001	.001	3	1
PDAC	SOD2 →	-1.048	-0.471	<.001	.001	3	1
PDAC	KHDRBS2 →	+0.510	+0.564	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 211 associations by consensus.

Exploration

KLHL17 survival (RNA) · tumor vs normal (RNA) · all KLHL17 data types