Across TCGA cell cohorts, KLHL17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,062 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KLHL17-associated GO terms across cancer lineages are DNA topological change, Regulation of mRNA splicing, via spliceosome, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with KLHL17 in more than 14 cancer types. Because this analysis shows association rather than direction, both KLHL17-to-partner and partner-to-KLHL17 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL17→partner) and Y-score (partner→KLHL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA topological change →	+0.172	+1.099	.001	.007	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.102	+1.490	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.159	+1.142	<.001	<.001	3	15
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.153	+1.283	<.001	<.001	3	15
BONE	Pre-mRNA catabolic process →	+0.218	+1.544	<.001	<.001	3	15
BONE	Telomere organization →	+0.109	+1.808	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,062 associations by consensus.

Exploration

KLHL17 survival (RNA) · tumor vs normal (RNA) · all KLHL17 data types