Across TCGA cell cohorts, KLHL17 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLHL17-associated genes across cancer lineages are PBOV1, TMEM82, and SLC32A1. Each is linked with KLHL17 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL17-to-partner and partner-to-KLHL17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL17→partner) and Y-score (partner→KLHL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PBOV1 →	+0.004	+3.475	<.001	.006	3	2
BLOOD_Lymphoma	TMEM82 →	+0.024	+4.643	<.001	.005	3	1
BLOOD_Leukemia	SLC32A1 →	+0.672	+4.223	<.001	.001	3	1
BLOOD_Leukemia	P2RX3 →	+0.063	+3.551	<.001	.008	3	1
BLOOD_Leukemia	IL4 →	+2.231	+4.007	<.001	.002	3	1
BLOOD_Leukemia	SLC5A7 →	+0.004	+3.922	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration

KLHL17 survival (RNA) · tumor vs normal (RNA) · all KLHL17 data types