Across TCGA patient cohorts, KLHL14 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,752 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL14-associated proteins across cancer lineages are TNXB, CARMIL2, and CARMIL2_S1381. Each is linked with KLHL14 in more than 4 cancer types. Because this analysis shows association rather than direction, both KLHL14-to-partner and partner-to-KLHL14 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL14→partner) and Y-score (partner→KLHL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TNXB →	+0.608	+0.645	.003	<.001	3	5
CCRCC	CARMIL2 →	+0.615	+0.942	.007	.007	3	4
LSCC	CARMIL2_S1381 →	+1.207	+0.647	<.001	.006	3	4
LSCC	ABCA8 →	+0.533	+0.600	<.001	<.001	3	4
LSCC	CORO2B →	+0.513	+0.402	<.001	<.001	3	4
PDAC	AKAP12_S441 →	+0.587	+0.507	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,752 associations by consensus.

Exploration

KLHL14 survival (RNA) · tumor vs normal (RNA) · all KLHL14 data types