Across TCGA cell cohorts, KLHL14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,397 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLHL14-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Positive regulation of double-strand break repair, and Oxidative phosphorylation. Each is linked with KLHL14 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLHL14-to-partner and partner-to-KLHL14 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL14→partner) and Y-score (partner→KLHL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of nucleotide-excision repair →	+0.093	+0.471	<.001	.007	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair →	+0.084	+0.090	<.001	.005	3	6
OVARY	Oxidative phosphorylation →	+0.109	+1.998	<.001	.001	3	6
BLOOD_Lymphoma	Spindle assembly →	+0.046	+1.228	.003	.004	3	6
BLOOD_Leukemia	Membrane invagination →	-0.082	-0.597	<.001	.001	3	6
LUNG_SCLC	Cell-matrix adhesion →	-0.129	-1.813	.001	.003	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,397 associations by consensus.

Exploration

KLHL14 survival (RNA) · tumor vs normal (RNA) · all KLHL14 data types