KLHL13

Across TCGA patient cohorts, KLHL13 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,110 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL13-associated proteins across cancer lineages are GSTM3, GSTA4, and ISG20. Each is linked with KLHL13 in more than 4 cancer types. Because this analysis shows association rather than direction, both KLHL13-to-partner and partner-to-KLHL13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL13 versus GSTM3 in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL13→partner) and Y-score (partner→KLHL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GSTM3 →	+1.301	+1.352	<.001	<.001	3	5
LSCC	GSTA4 →	+0.985	+1.071	<.001	<.001	3	4
LSCC	ISG20 →	-0.518	-1.111	<.001	.001	3	4
LSCC	MAP1B_T1282 →	+1.101	+0.950	<.001	<.001	3	4
UCEC	MPP6 →	+0.509	+1.515	<.001	<.001	3	4
LSCC	SOX6_S411 →	+1.007	+0.865	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,110 associations by consensus.

KLHL13 vs GSTM3 — LSCC

Explore this scatter interactively →