KLHL13

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KLHL13 protein abundance is significantly associated with the RNA expression of many other genes, with 5,578 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KLHL13-associated genes across cancer lineages are LDHAL6EP, HPN, and CD22. Each is linked with KLHL13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL13-to-partner and partner-to-KLHL13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL13 versus LDHAL6EP in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL13→partner) and Y-score (partner→KLHL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLDHAL6EP →+0.680+0.378.007.00632
LSCCHPN →-1.097-0.400.002.00132
GBMCD22 →-1.045-0.403.007.00132
GBMETS1 →+0.531+0.412.002<.00132
GBMFAM124A →-1.124-0.629<.001<.00132
LSCCSNHG16 →+0.376+0.405.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,578 associations by consensus.

KLHL13 vs LDHAL6EP — UCEC

Per-sample scatter of KLHL13 vs LDHAL6EP in UCEC (Pearson r = 0.34).

Explore this scatter interactively →

Exploration