KLHL13

Across TCGA cell cohorts, KLHL13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,401 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KLHL13-associated GO terms across cancer lineages are Cellular respiration, Aerobic respiration, and Proton motive force-driven mitochondrial ATP synthesis. Each is linked with KLHL13 in more than 11 cancer types. Because this analysis shows association rather than direction, both KLHL13-to-partner and partner-to-KLHL13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular respiration grouped by KLHL13-low versus KLHL13-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL13→partner) and Y-score (partner→KLHL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Cellular respiration →	+0.065	+1.330	<.001	.002	3	12
CNS	Aerobic respiration →	+0.074	+1.570	<.001	<.001	3	11
CNS	Proton motive force-driven mitochondrial ATP synthesis →	+0.089	+1.680	<.001	<.001	3	10
OESOPHAGUS	Nucleoside triphosphate biosynthetic process →	+0.096	+1.963	.004	.003	3	9
OESOPHAGUS	Ribonucleoside triphosphate biosynthetic process →	+0.110	+2.037	.001	.002	3	9
LUNG_NSCLC_LUSC	Mitochondrial electron transport, NADH to ubiquinone →	+0.111	+2.810	<.001	.004	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,401 associations by consensus.

Cellular respiration by KLHL13 expression — CNS

Explore this box plot interactively →