KLHL11

Across TCGA patient cohorts, KLHL11 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,052 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL11-associated proteins across cancer lineages are LIG3, TRIM28, and ZMYM3. Each is linked with KLHL11 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLHL11-to-partner and partner-to-KLHL11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL11 versus LIG3 in LSCC, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL11→partner) and Y-score (partner→KLHL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LIG3 →	+0.648	+0.868	<.001	<.001	3	7
GBM	TRIM28 →	+0.272	+0.268	<.001	<.001	3	7
GBM	ZMYM3 →	+0.342	+0.282	<.001	<.001	3	6
GBM	ZNF207 →	+0.276	+0.430	<.001	<.001	3	6
LSCC	ZNF830 →	+0.367	+0.747	<.001	<.001	3	6
HNSC	PRPF19 →	+0.264	+0.543	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,052 associations by consensus.

KLHL11 vs LIG3 — LSCC

Explore this scatter interactively →