KLHL11

Across TCGA patient cohorts, KLHL11 protein abundance is significantly associated with the RNA expression of many other genes, with 8,099 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL11-associated genes across cancer lineages are SOCS7, RUNDC3A, and RND2. Each is linked with KLHL11 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHL11-to-partner and partner-to-KLHL11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL11 versus SOCS7 in LSCC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL11→partner) and Y-score (partner→KLHL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SOCS7 →	+0.617	+0.148	<.001	<.001	3	3
BRCA	RUNDC3A →	+1.045	+0.182	<.001	.002	3	3
LSCC	RND2 →	+0.969	+0.142	<.001	.002	3	3
CCRCC	PLCXD2 →	-0.801	-0.351	<.001	<.001	3	3
LSCC	UBTF →	+0.486	+0.224	<.001	<.001	3	3
LSCC	DHX40 →	+0.493	+0.141	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,099 associations by consensus.

KLHL11 vs SOCS7 — LSCC

Explore this scatter interactively →