KLHDC7B

Across TCGA patient cohorts, KLHDC7B protein abundance is significantly associated with the RNA expression of many other genes, with 4,065 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHDC7B-associated genes across cancer lineages are CD70, APOL3, and CXCL10. Each is linked with KLHDC7B in more than 3 cancer types. Because this analysis shows association rather than direction, both KLHDC7B-to-partner and partner-to-KLHDC7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHDC7B versus CD70 in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC7B→partner) and Y-score (partner→KLHDC7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CD70 →	+1.294	+0.949	<.001	.002	3	4
LSCC	APOL3 →	+1.251	+1.605	<.001	.001	3	4
LUAD	CXCL10 →	+1.754	+1.406	.008	.001	3	4
LUAD	CXCL11 →	+2.337	+1.298	.003	.002	3	4
LUAD	PSMB9 →	+1.700	+2.285	<.001	.002	3	4
BRCA	IFIH1 →	+1.382	+1.108	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,065 associations by consensus.

KLHDC7B vs CD70 — HNSC

Explore this scatter interactively →