KLHDC7B

Across TCGA cell cohorts, KLHDC7B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,863 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible KLHDC7B-associated GO terms across cancer lineages are Response to endoplasmic reticulum stress, Regulation of response to endoplasmic reticulum stress, and Regulation of translation in response to endoplasmic reticulum stress. Each is linked with KLHDC7B in more than 13 cancer types. Because this analysis shows association rather than direction, both KLHDC7B-to-partner and partner-to-KLHDC7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to endoplasmic reticulum stress grouped by KLHDC7B-low versus KLHDC7B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC7B→partner) and Y-score (partner→KLHDC7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to endoplasmic reticulum stress →	+0.095	+3.040	<.001	.004	3	14
STOMACH	Regulation of response to endoplasmic reticulum stress →	+0.063	+0.891	<.001	.009	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of translation in response to endoplasmic reticulum stress →	+0.123	+1.484	.001	<.001	3	11
PANCREAS	Integrated stress response signaling →	+0.105	+1.520	<.001	<.001	3	10
URINARY_TRACT	Endoplasmic reticulum to cytosol transport →	+0.119	+2.067	<.001	.006	2	11
URINARY_TRACT	Retrograde protein transport, ER to cytosol →	+0.119	+2.067	<.001	.006	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,863 associations by consensus.

Response to endoplasmic reticulum stress by KLHDC7B expression — URINARY_TRACT

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