KLHDC7A

Across TCGA pan-cancer cohorts, KLHDC7A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KLHDC7A data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher KLHDC7A mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated KLHDC7A expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

CCRCC, PDAC, and UCEC are the cancer types where KLHDC7A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	1.000	0.877	.017	11	view →
PDAC	DFS	Median	II,III,IV	0.573	0.882	.013	10	view →
UCEC	DFS	Quartile	All	1.000	0.870	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KLHDC7A–CCRCC (OS)

Open the CCRCC breakdown →