KLHDC7A

Across TCGA cell cohorts, KLHDC7A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,281 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible KLHDC7A-associated GO terms across cancer lineages are Response to progesterone, Protein transport into membrane raft, and Regulation of atrial cardiac muscle cell membrane repolarization. Each is linked with KLHDC7A in more than 7 cancer types. Because this analysis shows association rather than direction, both KLHDC7A-to-partner and partner-to-KLHDC7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to progesterone grouped by KLHDC7A-low versus KLHDC7A-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC7A→partner) and Y-score (partner→KLHDC7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Response to progesterone →	+0.149	+2.537	.001	<.001	3	8
LUNG_NSCLC_LUAD	Protein transport into membrane raft →	+0.271	+0.570	.005	.001	3	8
BREAST	Regulation of atrial cardiac muscle cell membrane repolarization →	-0.358	-1.191	<.001	.004	3	7
BREAST	Negative regulation of urine volume →	+0.404	+0.828	.002	.006	3	7
URINARY_TRACT	Lipid catabolic process →	+0.052	+1.427	.003	.007	3	7
STOMACH	Positive regulation of CD4-positive, alpha-beta T cell activation →	+0.108	+0.917	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,281 associations by consensus.

Response to progesterone by KLHDC7A expression — KIDNEY

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