KLHDC3

Across TCGA patient cohorts, KLHDC3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,729 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHDC3-associated genes across cancer lineages are RRP36, NOL11, and CXorf56. Each is linked with KLHDC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHDC3-to-partner and partner-to-KLHDC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHDC3 versus RRP36 in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC3→partner) and Y-score (partner→KLHDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RRP36 →	+0.571	+0.330	.009	.002	3	3
OV	NOL11 →	+0.674	+0.497	.003	.003	3	2
OV	CXorf56 →	+0.542	+0.488	.002	.009	3	2
OV	TFRC →	+0.887	+0.488	.007	.009	3	2
HNSC	PLEKHG7 →	-0.481	-0.227	.009	.006	3	2
LSCC	LINC02605 →	-0.840	-0.244	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,729 associations by consensus.

KLHDC3 vs RRP36 — HNSC

Explore this scatter interactively →