KLHDC2

Across TCGA cell cohorts, KLHDC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,852 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLHDC2-associated GO terms across cancer lineages are Golgi vesicle transport, Vesicle coating, and Protein catabolic process at synapse. Each is linked with KLHDC2 in more than 13 cancer types. Because this analysis shows association rather than direction, both KLHDC2-to-partner and partner-to-KLHDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by KLHDC2-low versus KLHDC2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC2→partner) and Y-score (partner→KLHDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.071	+0.832	.003	.002	3	14
LUNG_SCLC	Vesicle coating →	+0.127	+0.679	<.001	<.001	3	12
STOMACH	Protein catabolic process at synapse →	+0.138	+0.733	.008	.009	3	11
STOMACH	Protein catabolic process at postsynapse →	+0.138	+0.733	.008	.009	3	11
LUNG_SCLC	Regulation of macroautophagy →	+0.040	+0.495	.002	.003	3	11
OESOPHAGUS	SRP-dependent cotranslational protein targeting to membrane, translocation →	+0.157	+1.323	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,852 associations by consensus.

Golgi vesicle transport by KLHDC2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →